⛳️ Thank you to our amazing sponsors for making the 12th Annual CNFWJ Atlanta Golf Classic a huge success! 🎉 🏌️♂️ We’re grateful to have you by our side in making a difference!
#CNFWJGolfClassic #ThankYouSponsors #GolfForACause
NTAP is #HIRING! Apply today to join the #NF team in this unique position, which involves seeing patients in the clinic and conducting research trials.
Being a part of @HopkinsMedicine has benefits. Search for REQ 115943 or 115950 https://jobs.jhu.edu/
Developing new approaches for NF1 therapeutics
Welcome to the Walker Lab! Our lab is based in the Center for Genomic Medicine at Massachusetts General Hospital. We are also a part of the Broad Cancer Program based at the Broad Institute.
Our research focuses primarily on neurofibromatosis type 1 (NF1), a genetic disorder with an incidence of one in 3,000–4,000 people. Most adults with NF1 develop neurofibromas – benign, but often disfiguring, tumors associated with peripheral nerves. About 10% of NF1 patients develop malignant peripheral nerve sheath tumors (MPNSTs), which carry a poor prognosis and are often fatal. However, NF1 is a chronic multi-system disorder affecting many different tissues with non-tumor symptoms including vascular and skeletal abnormalities, as well as cognitive deficits.
We utilize a combination of genetic, molecular and biochemical approaches and both animal and human cell models to improve our mechanistic understanding of NF1 and identify therapeutic targets. The laboratory is currently supported by funds from the National Institutes of Health, The Children’s Tumor Foundation (CTF), the Gilbert Family Foundation, and NF Northeast.
